Why am I unable able to run Syncfusion ASP.Net samples in IIS 6.0?
If you are using IIS 6.0 with UrlScan and IISLockdown with security limitation settings in urlscan.ini file, which contains a property that restrict the Period(".") symbol, i.e 'AllowDotInPath' is marked as '0' by default and this causes issue in running the samples. To fix this change the 'AllowDotInPath=1', it allows the usage of '.' operators in virtual directory file name.
The above issue also applies if you use any of the IIS version with UrlScan and IISLockdown.
Also please have a look at this KB