How to Reduce the File Size When Drawing TIFF Image in WinForms PDF?

//Create a PDF document
Syncfusion.Pdf.PdfDocument document = new Syncfusion.Pdf.PdfDocument();
document.PageSettings.SetMargins(0f);
//Load the image
using (System.Drawing.Image imageFile = System.Drawing.Image.FromFile("../../Data/image.tiff"))
{
FrameDimension frameDimensions = new FrameDimension(
imageFile.FrameDimensionsList[0]);
//Get frame count
int frameNumber = imageFile.GetFrameCount(frameDimensions);
for (int frame = 0; frame < frameNumber; frame++)
{
// Selects one frame at a time and save as Jpeg.
imageFile.SelectActiveFrame(frameDimensions, frame);
MemoryStream ms = new MemoryStream();
//save the frame as Jpeg image
using (Bitmap bmp = new Bitmap(imageFile))
{
ImageCodecInfo encoderInfo = this.GetEncoderInfo("image/jpeg");
EncoderParameters encoderParams = new EncoderParameters(1);
encoderParams.Param[0] = new EncoderParameter(Encoder.Quality, 50L);
bmp.Save(ms, encoderInfo, encoderParams);
bmp.Dispose();
}
ms.Position = 0;
//Load the Jpeg image
PdfBitmap image = new PdfBitmap(ms);
//Add the page
Syncfusion.Pdf.PdfPage page = document.Pages.Add();
//Create a PDF graphics
PdfGraphics g = page.Graphics;
//Draw the image into PDF page
g.DrawImage(image, new RectangleF(0, 0, page.GetClientSize().Width, page.GetClientSize().Height));
//Dispose the memory
ms.Dispose();
}
}
// Save and close the document.
document.Save("Output.pdf");
document.Close(true);